Randy Berholtz

Pennsylvania & Nuffield 1985

Born in Shamokin, Pennsylvania in 1961, Randy Berholtz studied at Cornell and went to Oxford on a scholarship before then winning the Rhodes Scholarship and staying on in Oxford for further study. He returned to the US to attend Yale Law School and went into legal practice in New York and then in Pennsylvania. In 1996, Berholtz moved to San Diego and began doing legal work for life sciences firms, later transitioning into venture capital within life sciences. He is currently a partner in Mesa Verde Venture Partners, which looks to create breakthrough companies that can bring scientific innovation to patients worldwide. This narrative is excerpted from an interview with the Rhodes Trust on 3 September 2025.  

‘I was a sponge’ 

I grew up in a small coal mining town. One side of my family was Pennsylvania Dutch while the other was Polish Catholic, so a large part of my upbringing was in this Polish Catholic household where I was the only Protestant kid. My father had very little education and went to work in the mines early. My mother was very smart and she was supposed to go to college but she missed graduating from high school by 3 months because she had to go out to work. I was very lucky in that education was very important to her.  

I was interested in learning and in playing sports. I always read the newspaper and I was a sponge: I just wanted to get as much information as I could. The one thing I could always do was write and I remember that we had one particularly whacky and brilliant teacher who would just encourage us to write poetry and to write fiction. This was 1973, and we wrote a lot about the Vietnam War. My cousin Bobby was in the Marines in Vietnam and had an honourable discharge after being wounded twice. It felt like I grew up in a place where if you didn’t go to college then you either went into the mines or into the military, and very few people went to college without having sports scholarships.  

On applying for the Rhodes Scholarship 

I went to Cornell and I was lucky that they had a scholarship that was based on the individual need of the applicant rather than on sports, because I kept getting injured. I studied politics and economics combined and it really gave me the framework to understand politics and business in government. I also took creative writing courses, because Cornell had a really good English department. Alongside that, I was also taking psych classes and having a lot of speech therapy too, because I grew up with a stutter.  

I didn’t really start thinking about the Rhodes Scholarship until my senior year. I had always known about Rhodes Scholars because of people like Bill Bradley (Missouri & Worcester 1965) and Pat Haden (California & Worcester 1975). I thought, ‘How can I compete against these guys?’’ But my writing meant that I knew how to tell a story and how to communicate. Even so, I remember going to have a sort of pre-interview with one of the professors at Cornell and I got there and just started stuttering and couldn’t finish. He said, ‘It’s okay, Randy. This is probably not for you,’ and I just felt devastated. I was lucky to get another scholarship for Oxford from Cornell and I went to Pembroke College. But when I was at Oxford, I said, ‘To hell with it. I’m going to apply for the Rhodes Scholarship.’ There were a few Rhodes Scholars at Pembroke and they sat down with me and effectively gave me some training sessions. I applied, and I go to the state interviews and it was probably one of the most daunting tasks you could have – all these brilliant people – but I said to myself, ‘You know what? You got this far. You can do it.’ I made it through to regionals and that was tough. I couldn’t believe it when they read out my name. It was a fantastic day. After they made the announcement, I remember I was calling everyone.  

‘It was a great experience, meeting people from around the world’ 

I stayed on at Pembroke after I’d won the Scholarship. Then, after law school, the Rhodes programme allowed me to come back to Oxford for another year and that’s when I went to Nuffield. I found that a lot of the other Rhodes Scholars were from upper-class backgrounds and not a lot of people talked to me, but I gravitated towards the athletes and the people who’d come from small towns, as I had, and some of the friends I met there are still my friends today.  

For the Rhodes, I did a master’s degree in politics, looking at a topic around the US Commission on Civil Rights. I had planned to do a doctorate, and I almost got it finished, but by then, my British wife and I had had our first baby, so I specialised instead in a British wife and British baby! 

I was in the Oxford Union debating society, and I actually ran for office in the Oxford Union. The first time, I lost to Michael Gove, who went on to be a senior minister in the British government. The second time, I won. I got to meet all sorts of people, including Boris Johnson, who would always tell us, ‘I’m going to be prime minister one day,’ and we were just, like, ‘Oh, come on, Boris.’  

It was a great experience, meeting people from around the world, and to me, that was as important as anything else at Oxford. It’s more than just the specific academics: some of the best conversations are the ones you have are over drinks or when you’re just walking around. 

‘It was putting me in a place I wouldn’t traditionally have been’ 

The truth is, I only really liked law in the first place because that’s what politicians did. I don’t think I had a good understanding or a good appreciation of what a lawyer actually did. I remember going to Yale Law School and thinking, ‘Wow, this is actually really interesting.’ My goal was to work for a law firm for a couple of years and then become the next Congressman from Pennsylvania. So, after finishing law school, I started working with Cravath, Swaine & Moore in New York City. I commuted in from Greenwich, Connecticut and I was working crazy hours, and it was terrible.  

So, I moved with my family to Pittsburgh and worked at Kirkpatrick & Lockhart, the law firm of our past governor, Richard Thorburgh. I was still planning to go into politics but we were there, and we were trying to have a second baby, when out of the blue, I found out I had testicular cancer. So, I had to focus. I had radiation therapy and chemo and surgery. Suddenly, politics didn’t seem to matter as much. It was about surviving. It just threw me, and I said to my wife, ‘I can’t be in Pennsylvania anymore. I’ve got to have a fresh start someplace else.’ And just a few months before I left, we had our second baby. 

We came out to San Diego in 1996, and we’ve been here ever since. I joined another law firm and then became in-house with a public life science company, working my way up to become General Counsel. I think that having cancer at such an early point in my life had made me appreciate the work done in life sciences. I thought, if I was going to focus on something, I should focus on something that could make a difference.  

In the early 2000s, I started working for a group of Chinese life science companies, and being there reminded me of the Rhodes Scholarship, in the sense that it was putting me in a place I wouldn’t traditionally have been. It was a great experience and I got to spend a lot of time in China and I also started teaching on the side at the law school and the business school in San Diego. I was even able to create a course on biotech law. One thing I’ve learned about myself is that I like to be entrepreneurial. Now, I have a cell therapy company and we’re just about to raise our first round of funding to try to create a functional cure for HIV. In fact, one of the key connections has been from the Rhodes network, connecting us with people handling HIV in South Africa. 

 

‘I pride myself on getting things done’ 

I think a lot of Rhodes Scholars are very similar, in that we’re not just academics, or entrepreneurs, or sportspeople. Alongside whatever we do, we’re focused on the community. Throughout my career, I’ve stayed interested in politics. I was a Democrat, but later, I became a Republican, and I’m part of a group trying to focus on policy issues that are good for the American working class. My big thing in politics is, I try to be true to myself and I pride myself on getting things done. To me, democracy is about debate and it’s about being uncomfortable sometimes but, like a company, it does take a lot of people to move towards a goal. I think the Rhodes Scholarship is about capturing that idea. It comes down to service.  

Transcript